turmeric, saw palmetto, Ginkgo Biloba, garlic, echinacea. Get info of suppliers, manufacturers, exporters, traders of Lycopene Capsule for buying in India. One clinical trial suggested that preventative use of lycopene supplements reduces the spread of localized prostate cancer, but there is no other proof from clinical trials that lycopene can treat cancer. Available for Android and iOS devices. May being the operative word. This information is not specific medical advice and does not replace information you receive from your health care provider. Lycopene administered as a pure compound has been studied in clinical trials at dosages of 8 to 75 mg/day.66, 80, 81, 82, 83, 84 Lycopene is primarily available in capsule and softgel form, with dosage guidelines from manufacturers ranging from 10 to 30 mg taken twice daily with meals. Puritans Pride Lycopene 20 Mg Softgels, 60 Count, Puritan's Pride Lycopene 40 mg, Supplement for Prostate and Heart Health Support**, Contains Antioxidant Properties**, 60 Rapid Release Softgels, Jarrow Formulas CarotenAll for Cardiovascular and Vision Health, 60 Soft gels, Puritans Pride Lycopene 10 Mg Softgels, 100 Count, NOW Supplements, Lycopene 20 mg with Natural Extract from Tomatoes, Free Radical Scavenger*, 50 Softgels, Lycopene & Lutein Complex 50MG 200 Veggie Capsules (Non-GMO & Gluten Free) Antioxidant Natural Tomato Great for Prostate Health, Immune System Support, Heart Health, Eyesight Support, NOW Supplements, Lycopene 10 mg with Natural Extract from Tomatoes, Free Radical Scavenger*, 60 Softgels, Lycopene 20mg Per Serving - 200 Capsules - Lycopene Supplement - Super Antioxidant which Helps Support Immune System and Prostate Health, Swanson Lycopene Supplement, Prostate Health Supplement 20 mg, 60 Softgels, Healthy Origins LYC-O-Mato Lycopene (Non-GMO) 15 mg, 180 Softgels, Lycopene 50mg 180 Vegetarian Capsules | Supplement for Prostate & Heart Health | Antioxidant Natural Tomato Extract Non-GMO | Supports Immune System & Helps Reduce Free Radical Damage - Pure Powder, Spring Valley - Lycopene 10 mg, 60 Softgels, Life Extension Mega Lycopene Extract 15 Mg, 90 softgels (00455), 2 Bottles Lycopene 50mg 180 Total Capsules KRK Supplements, Lycopene 50mg x 180 Tablets (6 Months Supply). Lycopene 20mg Per Serving - 200 Capsules - Lycopene Supplement - Super Antioxidant which Helps Support Immune System and Prostate Health 4.4 out of 5 stars 309 $19.99$19.99 ($0.10/Count) Get it as soon as Tue, Dec 15 Prime members enjoy FREE Delivery and exclusive access to music, movies, TV shows, original audio series, and Kindle books. Elimination of 1 study with wide confidence intervals revealed a significant inverse association between dietary intake as well as blood concentrations of lycopene and prostate cancer risk.108 A meta-analysis of 21 studies provided further evidence of diets rich in tomatoes providing protection against prostate cancer.19 In a Cochrane review of randomized controlled trials of lycopene for the prevention and treatment of benign prostatic hyperplasia and prostate cancer, only 3 of 64 published studies with 154 participants met inclusion criteria. However, after exclusion of breast cancer cases diagnosed during the first 2 years of follow-up, the association was no longer statistically significant.25 A pooled analysis of 8 prospective studies on carotenoids and breast cancer demonstrated a statistically significant inverse association between carotenoid levels, including lycopene concentrations, and the risk of breast cancer.26, In a large case-control study (N = 4,721) covering 3 years, the risk of pancreatic cancer for men consuming lycopene was reduced 31%. Special Precautions & Warnings: Pregnancy and breast-feeding: Lycopene is LIKELY SAFE during pregnancy and breast-feeding when taken in amounts commonly found in foods. The lycopene in supplements is about as easy for the body to use as lycopene found in food. 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In general, tomato-based products and lycopene supplements are well tolerated. Lutein Non GMO by Jiva Botanicals, Jarrow Formulas Lyco-Sorb, Supports Prostate & Cardiovascular Health, 10 mg, 60 Softgels, 50mg Lycopene x 360 Tablets (2 Bottles of 180 Tablets Each - 12 Months Supply). Get the best deals on Lycopene Capsule Vitamins & Minerals and stay healthy at home while you shop our large selection & lowest prices at eBay. Like beta-carotene, lycopene is a carotenoid. Select one or more newsletters to continue. 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It is the most abundant carotenoid in tomatoes (0.9 to 4.2 mg per 100 g), followed by beta-carotene, gamma-carotene, phytoene, and other minor carotenoids,4 and is touted as the highest overall single oxygen-quenching carotenoid, with double the value of beta-carotene.6, Lycopene is relatively resistant to heat-induced geometrical isomerization in tomato processing.7 Processed tomato products are a better source of lycopene than fresh tomatoes,8 with lycopene more bioavailable.9 In addition, human uptake of lycopene is greater from heat-processed tomato juice than from unprocessed tomato juice.10 Tomato sauce and ketchup contain 33 to 68 mg of lycopene per 100 g, and raw tomatoes contain 3.1 mg of lycopene per 100 g.4, 6 Mechanical treatment with heat helps release lycopene from the tomato matrix, improving bioavailability, as seen with processed commercial tomato products versus fresh tomatoes. Fast & Free shipping on many items! Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. For years, scientists noted that diets high in beta-carotene FROM FOOD SOURCES, reduced risk of many types of cancer, including lung cancer in smokers. Lycopene also protects your skin, thanks to its photoprotective properties. Lycopene was well tolerated; no serious adverse events were reported.106, A meta-analysis of 13 observational studies (n =18,999) evaluated the association between blood levels of antioxidants and vitamins to the risk of age-related cataract. Co-Enzyme Q10, Lycopene, Omega 3 Fatty Acid, Selenium, DHA, EPA, L-Carnitine And L-Tartrate Capsules - Buy Coenzyme Q10 at best price of Rs 50000/box from Innervate Lifesciences (A Unit Of Asvins Lifecare). The powerful antioxidant properties of lycopene fight free radicals and oxidative stress. Doses ranged from 4.5 to 15 mg/day (mean, 12.4 mg/day) for a duration of 4 to 16 weeks (mean, 8.3 weeks); average net change in SBP ranged from −11.5 to 2.4 mm Hg with an overall pooled estimate of −4.95 mm Hg. Updated hourly. Medically reviewed by Drugs.com. Triple Strength Lycopene are 3 x Strength of Regular Tablets. Lycopene absorption in humans is approximately 10% to 30%, with the remaining excreted.1 The half-life elimination of lycopene in plasma was estimated to be 12 to 33 days, while a single-dose pharmacokinetic study documented 28 to 61 hours.85 The estimated daily dietary intake of the general population is 0.5 to 27 mg per person per day.86 Factors affecting uptake and absorption of carotenoids have been reported.87 Pharmacokinetic parameters of lycopene have been evaluated in humans.39, 88, 89, 90, 91, 92, 93, 94, Information regarding safety and efficacy in pregnancy and lactation is lacking. Our most popular products based on sales. Excessive free radical damage has been implicated in the development of heart disease, Alzheimer’s disease and many cancers, as well as accelerated aging. There are several published studies that evaluate whether lycopene in tomato products or supplements could have protective effects against prostate cancer and cardiovascular disease. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. No toxic effects were observed in rats treated with lycopene 2,000 mg/kg/day for 28 days, an intake similar to approximately lycopene 200 mg/kg of body weight per day in humans.86 Another 13-week toxicity study generated similar results. Clinical studies evaluating the benefits of supplemental lycopene in pre-eclampsia have produced conflicting results, and some evidence of harm has been reported.95, 96 The amount of lycopene in foods is assumed to be safe. Lycogard Capsule is used for Vitamin a deficiency, Leg pain due to blocked arteries, Skin diseases, Skin infection, High blood pressure, For eye and ear wash, Uterine cancer, Red blood cell production, Eye problems, Wound healing and other conditions. One cup of canned tomato paste provides 75 mg of lycopene, compared to 5 mg in one cup of raw tomatoes, the Linus Pauling Institute notes. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Although numerous animal studies exist,4 only clinical evidence was reviewed in the following studies. The amount of lycopene in food is assumed to be safe. Lycopene is lipophilic and insoluble in water. Watermelon, pink, grapefruit, guava, apricots and papaya contain lycopene. Change in forearm blood flow from baseline, as measured by endothelium-dependent vasodilatation (EDV), improved significantly in CVD patients (63% higher; P = 0.008) with values that approximated those of healthy volunteers at baseline. Bottom Line Lycopene is a plant nutrient with antioxidant properties. Your body converts some carotenoids to retinol, a form of vitamin A. Lycopene has no vitamin A activity, but getting the recommended daily dose of this nutrient can provide antioxidant benefits that may help keep you healthy and feeling young. Reductions were most significant in Asian studies, for those with an initially higher baseline SBP (greater than 120 mm Hg), and with higher dosages (> 12 mg/day).103 Similar results were found from a meta-analysis of 4 intervention trials published between 1955 and 2010.109, The effects of oral lycopene supplementation on vascular function was investigated in a randomized, double-blind, placebo-controlled trial with parallel arms including statin-treated patients with cardiovascular disease (CVD; n = 36) as well as healthy volunteers (n = 36). In 1 study, lycopene inhibited human colon carcinoma, myeloid leukemia, and lymphoma cell lines in a dose-dependent manner.3 Lycopene and eicosapentaenoic acid also suppressed signal transduction pathways in human colon cancer cells, thus inhibiting cancer cell growth.20 Another study documented activity against a liver adenocarcinoma cell line and noncancerous lung cell line.2 Lycopene prevented chemically induced DNA and chromosome damage as well as tumor-promoting activity in liver cells through antioxidant activity and inhibition of growth factors and signaling pathways.21, 22, 23, In a clinical trial, lycopene supplementation (30 mg/day for 2 months) had beneficial effects in healthy women with a high risk of breast cancer (n = 36) but not in breast cancer survivors (n = 24).24 In a longitudinal study in which serum levels of various carotenoids and micronutrients were measured in a subset of women from the Women’s Health Initiative clinical trials (N = 5,450), higher baseline levels of lycopene were associated with an increased risk of invasive breast cancer during a median follow-up of 8 years. Last updated on Jan 20, 2020. Top subscription boxes – right to your door, © 1996-2020, Amazon.com, Inc. or its affiliates. Lycopene administered as a pure compound has been studied in clinical trials at dosages of 7 to 75 mg/day. Lycopene suppressed tissue factor activation in vascular thrombosis in human endothelial cells.41 Additional studies found that lycopene reduced expression of cell surface adhesion molecules and binding of monocytes.42, 43 Lycopene also bound and inhibited platelet-derived growth factor, which is associated with the development and progression of cardiovascular disease in rat smooth muscle cells.44 One nutritional study in rabbits compared lycopene's action in reducing the formation of atherosclerotic plaques in the aorta with that of fluvastatin.45 There are studies on the development of more efficient vehicles to deliver lycopene to adipocytes.46, In 19 subjects, lycopene supplementation decreased serum lipid peroxidation and low-density lipoprotein (LDL) oxidation, suggesting a decreased risk for coronary heart disease.47 An epidemiological study in 10 European countries confirmed beneficial effects on the heart correlating with lycopene lipid levels and reduced risk of myocardial infarction.48 The Austrian Stroke Prevention Study found that certain concentrations of lycopene and other antioxidants may protect against cognitive impairment.49 Plasma LDL cholesterol concentrations were reduced by 14% in 6 men consuming dietary supplements of lycopene 60 mg/day for a 3-month period.50 In a 6-week clinical trial, 24 patients receiving fresh tomato and tomato juice twice daily reported reduced triglyceride levels and LDL cholesterol and increased high-density lipoprotein (HDL) cholesterol.51 In studies conducted in overweight individuals, both dietary and supplemental lycopene led to an increase in HDL cholesterol levels52 and a reduction in HDL-associated inflammation.53 In another study, low lycopene concentrations were associated with carotid atherosclerosis in 220 asymptomatic individuals.54, When the effects of tomato extract supplementation were studied in 50 moderately hypertensive individuals, supplementation for 6 weeks was associated with reduced systolic and diastolic blood pressure (SBP and DBP, respectively) and increased serum lycopene levels.55 A meta-analysis of 6 blinded intervention studies (N = 494) evaluating the effects of lycopene or lycopene-containing products on blood pressure found that lycopene supplement decreased SBP significantly (P = 0.012) but not DBP. This product may adversely interact with certain health and medical conditions, other prescription and over-the-counter drugs, foods, or other dietary supplements. As a result of this striking color, it is actually approved for use as a food coloring. In some countries, the tomato was thought to be poisonous and used for decorative purposes only. Participants received lycopene 7 mg or placebo daily for 2 months. Some GI complaints (eg, diarrhea, dyspepsia, gas, nausea, vomiting) are documented. One report found beta-carotene to be active in wound healing, while lycopene was inactive.62 Other studies document that lycopene or tomato-derived products rich in lycopene provide photoprotective effects against ultraviolet light-induced erythema.63, 64, 65 Higher levels of lycopene antioxidants in the skin effectively led to lower levels of skin roughness.15 In a placebo-controlled study, lycopene effectively managed oral lichen planus.66, In some animal models, lycopene reduced diabetes-induced learning and memory impairment by decreasing oxidative stress and inflammation.67 Lycopene may also attenuate diabetic neuropathic pain by inhibiting action of tumor necrosis factor (TNF)-alpha and nitric oxide.68 Lycopene may be useful in patients with type 2 diabetes by suppressing oxidative stress and enhancing innate immunity or serum levels of immunoglobulin M.69, Reports are available in the International Symposia on Lycopene and Tomato Products in Disease Prevention.70, 71 Reviews describing lycopene and disease prevention are also available.72, 73, 74, 75, Epidemiological studies have found that lycopene decreased the inflammation marker C reactive protein.13 The production of inflammatory mediators, such as TNF-alpha, was reduced in patients consuming a tomato-based drink.76 Asthmatic adults receiving lycopene treatment experienced improvement in airway inflammation. Other sources include apricots, cranberries, grapes, pink grapefruits, guavas, papayas, peaches, and watermelons.2, In North America, nearly 85% of dietary lycopene is derived from tomatoes and tomato-based products.1 Tomatoes have been cultivated since the 16th century as a food source. Lycopene is also incorporated in multivitamin and multimineral products. Additionally, no dose relationship was observed.110. Lycopene is also incorporated in multivitamin and multimineral products. In a review of epidemiologic studies, a diet rich in fresh tomatoes, tomato sauce, and pizza reduced the incidence of prostate cancer in a cohort of 40,000 men.19 Increased consumption of tomatoes statistically lowered the risk of prostate cancer in a cohort of 14,000 Seventh-day Adventist men.4, 28 A 2015 systematic review and dose-response meta-analysis of observational studies evaluating dietary intake (n = 13 studies) or blood concentrations (n = 15 studies) of lycopene on the risk of prostate cancer found a reduction in risk by 3% per 1 mg/day increment of dietary intake of lycopene. This is because lycopene might slow blood clotting. No significant changes in EDV were observed with placebo. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. There are numerous studies on the uses of lycopene in treating cancer and cardiovascular disease, as well as on its antioxidant and anti-inflammatory activity. Lycopene is responsible for the bright red color in certain foods such as tomatoes. Information regarding safety and efficacy in pregnancy and lactation is lacking. They combat inflammation, thereby preventing serious ailments like cancer and heart disease. Lycopene Claims The Science (or Lack Thereof) Behind Lycopene Word on the Street About Lycopene The Bottom Line: Are Lycopene Supplements Worth a Try? We comply with the HONcode standard for trustworthy health information -. Avoid with hypersensitivity to lycopene or to any of its food sources, especially tomatoes. Gardian Capsules - Cipla Lycopene Choline DL-Methionine Green Tea Extract Selenium Vitamin B12 (Cyanocobalamin) Vitamin B6 (Pyridoxine Hydrochloride) Vitamin C (Ascorbic Acid) Vitamin E Gardian Tablets - Cipla Lycopene Chromium (Chromium Picolinate) Copper (Copper Sulfate) Lycopene administered as a pure compound has been studied in clinical trials at dosages of 8 to 75 mg/day.66, 80, 81, 82, 83, 84 Lycopene is primarily available in capsule and softgel form, with dosage guidelines from manufacturers ranging from 10 to 30 mg taken twice daily with meals. Certain groups, like people on blood-thinning or blood pressure medications and pregnant women, should avoid using lycopene from dietary supplements. Gardian Capsules is mainly associated with symptoms and indications-The International Classification of Diseases (ICD)- A11AA03-Multivitamins and … Daily supplements containing up to 120 mg of lycopene have been used safely for up to one year. Check price at AmazonNOW Lycopene keeps it basic, but this formulation has a solid dosage of 20 mg of lycopene per capsule, which is delivered in rice bran oil and a gelatin capsule. Lycopene extract is usually low in cost and readily available in most health food stores. Lycopene's efficient absorption from tomato products facilitates its antioxidant effects and may also play an important role in cancer prevention.36 Lycopene not only achieves high concentrations in the prostate, but also in the testes and adrenal glands. Is known for to 120 mg of lycopene Capsule provider to ensure the information displayed on page... The risks and benefits of using this product by mouth in appropriate amounts and papaya contain lycopene POSSIBLY … powerful! Right to your personal circumstances cost and readily available in most health food stores, thereby serious. ( 2 Bottles of 180 Tablets Each - 12 Months Supply ) 120 mg of Capsule! 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